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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPR1
All Species:
26.36
Human Site:
S818
Identified Species:
52.73
UniProt:
P16066
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16066
NP_000897.3
1061
118919
S818
N
I
L
D
N
L
L
S
R
M
E
Q
Y
A
N
Chimpanzee
Pan troglodytes
XP_001168194
1047
116964
L803
S
I
L
D
N
L
L
L
R
M
E
Q
Y
A
N
Rhesus Macaque
Macaca mulatta
XP_001085221
1047
116990
L803
S
I
L
D
N
L
L
L
R
M
E
Q
Y
A
N
Dog
Lupus familis
XP_547577
1060
118154
S817
N
I
L
D
N
L
L
S
R
M
E
Q
Y
A
N
Cat
Felis silvestris
Mouse
Mus musculus
P18293
1057
119091
S814
N
I
L
D
N
L
L
S
R
M
E
Q
Y
A
N
Rat
Rattus norvegicus
P18910
1057
118933
S814
N
I
L
D
N
L
L
S
R
M
E
Q
Y
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517544
743
84256
L530
K
R
K
A
E
A
L
L
Y
Q
I
L
P
H
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083703
1056
120483
S813
N
I
L
D
N
L
L
S
R
M
E
Q
Y
A
N
Zebra Danio
Brachydanio rerio
NP_001038402
1067
121798
S825
N
I
L
D
N
L
L
S
R
M
E
Q
Y
A
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07553
1163
130896
S815
N
I
F
D
N
M
L
S
I
M
E
K
Y
A
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09435
1137
128085
N840
N
L
M
D
H
V
F
N
M
L
E
E
Y
T
S
Sea Urchin
Strong. purpuratus
P16065
1125
126238
A856
N
I
L
D
N
M
I
A
I
M
E
R
Y
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.2
61.2
91.6
N.A.
90.8
90.8
N.A.
48.5
N.A.
66.1
62.7
N.A.
31.5
N.A.
29.8
35.1
Protein Similarity:
100
73.8
73.8
95
N.A.
94.2
94.2
N.A.
58.6
N.A.
78.7
77.5
N.A.
47.8
N.A.
49
50.8
P-Site Identity:
100
86.6
86.6
100
N.A.
100
100
N.A.
6.6
N.A.
100
100
N.A.
66.6
N.A.
26.6
60
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
100
N.A.
13.3
N.A.
100
100
N.A.
80
N.A.
80
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
0
9
0
0
0
0
0
75
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
92
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
9
0
0
0
0
0
92
9
0
0
0
% E
% Phe:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
84
0
0
0
0
9
0
17
0
9
0
0
0
0
% I
% Lys:
9
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% K
% Leu:
0
9
75
0
0
67
84
25
0
9
0
9
0
0
0
% L
% Met:
0
0
9
0
0
17
0
0
9
84
0
0
0
0
0
% M
% Asn:
75
0
0
0
84
0
0
9
0
0
0
0
0
0
75
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
67
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
67
0
0
9
0
0
0
% R
% Ser:
17
0
0
0
0
0
0
59
0
0
0
0
0
0
17
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
9
0
0
0
92
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _